Originator: Biogen Idec
First marketed by: The Medicines Company UK Ltd.
Name of FDF: Angiox®, Angiomax®
Original FDF: Powder for reconstitution and IV injection
Other FDF: RTU solution
Mode of Action
Thrombin inhibitor. Inhibition of both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation.
Acute coronary syndromes; Heparin-induced thrombocytopenia and thrombosis syndrome; Thrombosis; Unstable angina pectoris
Generic products are available, a RTU formulation is still patented until 2029-08-20