Discovery Technologies

Bern headquarters

Discovery of novel Actives

AI assisted, computerized actives discovery incl. Target Identification, Hit Discovery & Lead Optimization based on more than two decades of unmatched peptide modeling know-how and access to the world largest, proprietary database of Peptide chemical space and novel Peptide actives

Zhangzhou Site

Peptide Custom synthesis

Rapid access to your peptide samples

Peptide classes include difficult to synthesize peptides incl. cyclic peptides, branched peptides, peptide dendrimers, chemically modified peptides

Synthesis of long chain peptides (up to 80-mers)

Peptide Drug Conjugates incl. drug/linker coupling technology, cyclic peptide synthesis, phosphorylation, fluorescence labeling, radionuclides, polyethylene glycol, alkylation, and various PDC coupling technologies

Liquid Phase Peptide Synthesis toolkit for shorter peptides incl. “Tag Assisted Liquid Phase Peptide Synthesis” combining the benefits of SPPS and LPPS

Xiamen Site

Preclinical Research Center

Broad technology platform for the preclinical development of novel drug candidates

Wide range of disease animal models incl. metabolic disorders like obese,hyperlipidemia,diabetes,MASH;Tumor including lung cancer, breast cancer, gastric cancer, etc.;Inflammation like osteoarthritis; Neurological disease include depression, schizophrenia, etc. Other diseases including infections, fibrosis

Safety Evaluation incl. single-dose/multiple-dose toxicity analysis; multi-species (human-inclusive) blood analysis; H&E histopathological analysis; in vivo biochemical analyses, etc.

Comprehensive in-vitro evaluation incl. cell culture,primary cells isolation,WB, IF, FCM, Elisa,CoIP,biochemical analysis,SRP,molecular cloning

Drug Metabolism & Pharmacokinetics incl. in-vitro and in-vivo half-life analysis, bioavailability analysis, and related assessments.

Formulation R&D center

One-stop shop covering the whole process of peptide formulation R&D

Pharmaceutical Formulation Development incl. lyophilized powders, microencapsulation, tablets, gels & creams, prefilled syringes, patches etc.

Customized formulations based on our clients formulas or specifications

Technical support and consultation for formulation development, process optimization, production process improvement, etc.