Sustainable Peptide Manufacturing

Bern, October 31, 2025.

Space Peptides Advances Green Chemistry Initiative by Replacing Acetonitrile with Ethanol in Semaglutide Purification Process

Space Peptides, a leading global Peptide CRDMO known for its premium speed and quality, today announced a breakthrough in sustainable pharmaceutical manufacturing: the successful partial replacement of Acetonitrile with Ethanol in the purification process of Semaglutide.

This initiative—part of Space Peptides’ ongoing Green Chemistrys Program—marks a significant reduction in the use of Acetonitrile, cutting toxic solvent consumption by 50%, and replacing the balance with biodegradable, environmentally harmless ethanol.

This transition drastically reduces the environmental impact, enhances process safety, and supports Space Peptides’ alignment with the United Nations Sustainable Development Goals (SDGs) while delivering a triple sustainability impact:

  1. Environmental Sustainability – Reduces toxic solvent use at the source, significantly lowers environmental footprint, and supports global green chemistry commitments.
  2. Operational Sustainability – Builds a greener, more independent supply chain, minimizing reliance on high-risk raw materials and ensuring stable long-term production.
  3. Business Sustainability – Strengthens Space Peptides’ leadership in ESG-driven innovation and enhances its brand as a responsible partner in the global biopharma ecosystem.

Dr. Josef Schröer, Chief Commercial Officer of Space Peptides, emphasized the broader relevance of this achievement:

“This transformation exemplifies how sustainability and commercial performance can reinforce each other. By integrating green chemistry at the core of production, we not only protect our environment but also strengthen the long-term value proposition for our clients worldwide.”

About Space Peptides:

Headquartered in Switzerland with global operations, Space Peptides provides end-to-end pharmaceutical Peptide CRDMO services—covering discovery, process development, and GMP manufacturing. With a strong commitment to innovation, quality, and sustainability, Space Peptides is shaping the future of peptide therapeutics manufacturing.

Learn more at http://spacepeptides.com

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