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PEPTIDES COMPANION

Space Peptides / a SPACE PHARMACEUTICALS company

Custom peptides synthesis

Custom peptides synthesis for Pre-GMP development

Space Peptides delivers custom peptides and peptide libraries at high quality, speedy timeline and in a cost-effective manner. Our custom synthesis capabilities apply to a broad range of peptides, including challenging and difficult peptides such as those with very long sequences (~ 70 amino acids in length and above), complex structures (e.g., cyclic, bicyclic, tricyclic peptides, peptide dendrimers), custom modifications and conjugates.

We understand the importance of quality for your research and preclinical development. Most of our custom synthesis peptides delivered till date have a purity of >95%, at miligram (mg) to kilogram (kg) scale. Our standard analytical methods determine purity by HPLC and mass-spectrometry.

Custom peptide modifications

We perform a broad variety of peptide modification, some of these modifications include:

  • Lactam-bridged and Thioether-linked cyclic peptides
  • FRET Peptides
  • Stable isotope-labeled Peptides 
  • Stapled peptides
  • Cyclic Peptides (Mono-cyclic, bi-cyclic and tri-cyclic peptides)
  • Peptide Dendrimers
  • Lipidated Peptide Dendrimers
  • Conjugated peptides 
  • Fluorescent and Dye Labelled peptides
  • Cyclic peptides with multiple disulfide bonds
  • Peptide PEGylation 
  • Peptide Glycosylation, Phosphorylation and Sulfation
  • Peptides with Fluorescent amino acids
  • Peptide with Unnatural variants (unnatural amino acids and other building blocks)
  • Lipidated Peptides
  • Branched Peptides
  • N-Terminal and C-Terminal modified Peptides
  • Peptidomimetics
  • Long Hydrophobic Peptides
  • Peptide Libraries
  • Depsipeptides

 

Chemistry, Manufacturing, and Control (CMC) Services

We build long-term partnerships with our customers, providing CMC services from simple short peptides to the most complex peptidomimetics, across all stages of the drug development lifecycle. We advise on the most suitable peptide synthesis technologies suitable to your specific projects, including solid phase peptide synthesis (SPPS), liquid phase peptide synthesis (LPPS), or hybrid approaches. We also support your needs on scale-up processes and technology transfer. 

We provide a variety of CMC services such as:

  • Synthetic route design 
  • Process development
  • Process optimization
  • Process validation
  • Analytical method development
  • Analytical method quantification
  • Analytical method validation
  • Product Characterization
  • Identification of impurities
  • Stability programs
  • Scale up

 

Get a quote today!

100% satisfaction or money-back guarantee

Figures: Space Peptides GMP pilot site in Xiamen, China, has obtained Chinese Food and Drug Administration (CFDA) certification and has a total capacity of 50kg/year.